Acute Kidney Injury (AKI) in Renal Transplant

Yilin Zhang, MD
Expert review by Raimund Pichler, MD (University of Washington, Division of Nephrology) and Iris De Castro, MD (University of Washington, Transplant Nephrology)

OBJECTIVES:

  1. Differentiate between pre-renal, intra-renal, and post-renal causes of acute kidney injury in a patient with a kidney transplant
  2. Name transplant specific complications that result in acute kidney injury
  3. Evaluate a patient with acute allograft dysfunction

TEACHING INSTRUCTIONS:


INTERACTIVE BOARDS

Use for Self-Directed Learning and Preparing to Present

Use For Presenting (Less Text and Fewer Pop-ups)


TAKE HOME POINTS:


REFERENCES:

  1. Goldberg, RJ, Weng, FL, & Kandula, P. 2016. Acute and Chronic Allograft Dysfunction in Kidney Transplant Recipients. Medical Clinics of North America. 100 (3):487-503
  2. Kadambi, PV, Brennan, DC & Chon, JW. Evaluation and diagnosis of the patient with renal allograft dysfunction. Lam, AQ, ed. UpToDate. Waltham, MA: UpToDate Inc. http://www.uptodate.com (Accessed on October 20, 2017.)
  3. Vella, J & DC. Hypertension after renal transplantation. Lam, AQ, ed. UpToDate. Waltham, MA: UpToDate Inc. http://www.uptodate.com (Accessed on October 20, 2017.)
  4. Limaye, AP &B Brennan, DC. Clinical manifestations and diagnosis of BK virus-induced (polyomavirus-induced) nephroatphy in kidney transplantation. Lam, AQ & Thorner, AR, eds. UpToDate, Inc. http://www.uptodate.com (Accessed on October 20, 2017.)
  5. Santos, CAQ, Vella, J & Brennan, DC. Clinical manifestations, diagnosis, and management of cytomegalovirus disease in kidney transplant recipients. Lam, AQ & Bond, S, eds. UpToDate, Inc. http://www.uptodate.com (Accessed on October 20, 2017.)
  6. Bennet, WM. Cyclosporine and tacrolimus nephrotoxicity. Lam, AQ, ed. UpToDate, Inc. http://www.uptodate.com (Accessed on October 20, 2017.)
  7. Hatlen, T et al. Disseminated Adenovirus Nephriis After Kidney Transplantation. Kidney Int Rep. 2018 Jan; 3(1): 19–23.