Inpatient Antibiotics, Part 2: Common Sites of Infection

OBJECTIVES:

  1. Name pathogenic bacteria implicated in common infections (pneumonia, UTI, intra-abdominal and skin and soft tissue)
  2. Propose empiric antibiotic regimens for these common sites of infection


Pneumonia: Interactive Board 

UTI:

Skin and Soft Tissue Infections: Interactive Board

Intra-abdominal Infections:

Final Board:

REFERENCES:

  1. Gilbert, DN, et al. (2017). Sanford guide to antimicrobial therapy 2017. Retrieved from: http://webedition.sanfordguide.com
  2. Mandell, LA et al. Infectious Diseases Society of America/American Thoracic Society Consensus Guidelines on the Management of Community-Acquired Pneumonia in Adults. Clinical Infectious Diseases. 2007; 44:S27–72
  3. Kalli, AC et al. Management of Adults With Hospital-acquired and Ventilator-associated Pneumonia: 2016 Clinical Practice Guidelines by the Infectious Diseases Society of America and the American Thoracic Society. Clinical Infectious Diseases. 2016; 63(5):e61–111.
  4. Marik, PE. Aspiration Pneumonitis and Aspiration Pneumonia. NEJM. 2001. 344(9): 665-671.
  5. DiBardino, DM & Wunderink, RG. Aspiration pneumonia: A review of modern trends. Journal of Critical Care. 2015, 30: 40-48.
  6. Gupta, K et al. International Clinical Practice Guidelines for the Treatment of Acute Uncomplicated Cystitis and Pyelonephritis in Women: A 2010 Update by the Infectious Diseases Society of America and the European Society for Microbiology and Infectious Diseases. Clinical Infectious Diseases. 2011; 52(5): e103–e120.
  7. Hootn, TM et al. Diagnosis, Prevention, and Treatment of Catheter- Associated Urinary Tract Infection in Adults: 2009 International Clinical Practice Guidelines from the Infectious Diseases Society of America. Clinical Infectious Diseases. 2010; 50:625–663
  8. Sievert, DM et al. Antimicrobial-Resistant Pathogens Associated with Healthcare-Associated Infections: Summary of Data Reported to the National Healthcare Safety Network at the Centers for Disease Control and Prevention, 2009–2010. Infect Control Hosp Epidemiol. 2013 ;34(1): 1-14.
  9. Stevens, DL et al. Practice Guidelines for the Diagnosis and Management of Skin and Soft Tissue Infections: 2014 Update by the Infectious Diseases Society of America. Clinical Infectious Diseases. 2014; 59(2): e10–52.
  10. Anaya, DA & Dellinger, EP. Necrotizing Soft-Tissue Infection: Diagnosis and Management. Clinical Infectious Diseases. 2007; 44: 705–10.
  11. Solomkin, JS et al. Diagnosis and Management of Complicated Intra-abdominal Infection in Adults and Children: Guidelines by the Surgical Infection Society and the Infectious Diseases Society of America. Clinical Infectious Diseases 2010; 50:133–64

Inpatient Antibiotics, Part 1: Spectrum

This chalk talk reviews the spectrum of activity of commonly used inpatient antibiotics. The second part of the talk then explores the microbiology of common infections (e.g., pneumonia, UTI, skin and soft tissue) and challenges the learner to apply their knowledge of antibiotic spectrums of activity to come up with empiric antibiotic regimens for these sites of infection.