AKI in a Patient with a Renal Transplant

The entire talk will take ~30-45 min.

• Differential Diagnosis: (5 min) Build a framework for a general approach to AKI. Click on “what is your differential” which will bring up the categories of prerenal, intrarenal, and postrenal etiologies. In patients with kidney transplants, these can be further separated into transplant specific causes and typical causes (click on the category buttons to reveal the differential for each). Very quickly ask your learners to call out some non-transplant causes of AKI in pre/intra/postrenal categories (click on the “differential?” button to reveal the differential. This should take no more than 2 min. Then ask for transplant specific causes. Remind your learners that while there are transplant specific complications, it's still important to include non-transplant causes in their differential. 
• Timeline: (15-30 min) Discuss that timing from transplant can help narrow guide your differential. You can click on any of the category or timeline buttons, though we suggest moving from “1 week” to “3 months” to “6 months” categories. After you reveal each of the different causes of AKI in their respective pre/intra/postrenal categories, click on specific causes (the arrows) to discuss the clinical presentation, laboratory findings, and diagnosis in depth. You may choose to only highlight a few of them. At the end, click on the “toolbox” icon to review the additional tests that are in your “toolbox” when evaluating someone with AKI in a renal transplant.
  
• Cases: (10-15 min) Practice cases. Put the framework you taught into use! Click on each case to reveal the case stem. Ask your learners to choose from tests in your toolbox and click each test button to reveal the underlying cause. Not all tests may be necessary in all cases.  Click the “diagnosis” to reveal the answer.